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KMID : 0370819930080010107
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Yonsei Journal Dental Science
1993 Volume.8 No. 1 p.107 ~ p.126
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The Effect of Aloe Vera And A Decalcified Freeze-Dried Bone Allograft on The Healing of The Horizontal Alveolar Defects In Dogs
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Abstract
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Regeneration of periodontal tissue after a loss of attachment due to disease or trauma repesents an important issue in dentistry, and various bone graft materials have been used to regenerated lost periodontal tissue and restore proper functions.
Among
those, allografts have been extensively researched and widely used clinically, since they are known to possess an excellent osteoinduction capability and result in proper topography of alveolar bone. Aloe vera has also been shown to aid tissue
healing
and reduce pain.
Regeneration of periodontal tissue in supraalveolar defects may be technically difficult. However, a large amount of regeneration has been observed by complete tissue coverage of involved teeth.
In this stud, supraalveolar defects in adult dogs were treated with periodontal surgery, decalcified freez-dried bone allograft and Aloe vera, complete tissue coverage was attained, and effects on repair and regeneration of alveolar bone,
cementum
and
periodontal ligament were studied. Exposure of premolar furcation of adult dogs was attained by removing marginal alveolar bone down to 5mm from CEJ, and root surfaces were planed with curettes. On the left side, defects were treated without any
allograft9Control Group), or with Aloe vera alone(Experimental Group I). On the right side, a combination of DFDB and Aloe vera was used(Experimental Group II). In all groups, flaps were coronally positioned and sutured, completely submerging the
treated defects.
@ES Healing progresses were histologically observed after eight weeks and the results were as follows :
@EN 1. The amount of alveolar bone formation was ; 0.76 ±0.72m in the control group, 0.41±0.46mm in experimental group I, and 1.93±0.54mm in experimental group II, with significant differences between various groups.(P<0.01).
2. The amount of cementum formation was : 1.60±0.65mm in the control group, 1.36±0.62mm in experimental group I, and 1.96±0.54mm in experimental group II, with no significant differences between various groups.
3. Connective tissue adhesion was; 0.58±0.57mm in the control group, 0.51±0.43mm in experimental group I, and 0.64±0.47mm in experimental group II, with no significant differences between various groups.
4. Connective tissue healing was ; 1.43±0.52mm in the control group, 1.46±0.84mm in experimental group I, and 0.68±0.59mm in experimental group II, with significant differences between various groups. (P<0.05) Orientation of connective tissue
fibers
in relation to root surfaces was ; mostly parallel in the control group, parallel or irregular in group I, and irregular or vertical in group II.
5. Gingival recession was ; 2.82±0.66mm in the control group, 3.13±0.58mm in experimental group I, and 2.40±0.68mm in experimental group II, with no significant differences between various groups.
6. Root resorption was observed larger in experimental group II than in other two groups.
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KEYWORD
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